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The N-terminal methionine oxidizes, creating methionine sulfoxide that alters binding kinetics

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As this is the first study to assess such measures, the predictive value of these markers will become even more solidified as future studies are completed and similar protein concentrations can be compared on new and even larger populations from the DRC, as well as konzo affected communities in other countries of sub-Saharan Africa

That number landed below the 25% target that Novo Nordisk had projected, causing brief concern among investors, but it still represents one of the largest weight loss outcomes ever achieved with a pharmacological intervention

Shan Y, Lee M, Chang EB (2022) The gut microbiome and inflammatory bowel diseases